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Biotechacademy.dkDTU.dkIndexContactPhonebook
Biotech Academy
System.Xml.Xsl.XsltException: Cannot find the script or external object that implements prefix 'util'. at System.Xml.Xsl.XsltCompileContext.ResolveFunction(String prefix, String name, XPathResultType[] argTypes) at System.Xml.XPath.XsltFunction.get_Function() at System.Xml.XPath.XsltFunction.ReturnType() at System.Xml.XPath.XsltFunction.get_Function() at System.Xml.XPath.XsltFunction.ReturnType() at System.Xml.XPath.XPathNavigator.Evaluate(XPathExpression expr, XPathNodeIterator context) at System.Xml.Xsl.Processor.ValueOf(ActionFrame context, Int32 key) at System.Xml.Xsl.ValueOfAction.Execute(Processor processor, ActionFrame frame) at System.Xml.Xsl.ActionFrame.Execute(Processor processor) at System.Xml.Xsl.Processor.Execute() at System.Xml.Xsl.XslTransform.Transform(XPathNavigator input, XsltArgumentList args, TextWriter output, XmlResolver resolver) at Sitecore.WebControls.XslFile.DoRender(HtmlTextWriter output) Xsl file could not be processed: /xsl/menu/topmenu.xslt
System.Xml.Xsl.XsltException: Cannot find the script or external object that implements prefix 'util'. at System.Xml.Xsl.XsltCompileContext.ResolveFunction(String prefix, String name, XPathResultType[] argTypes) at System.Xml.XPath.XsltFunction.get_Function() at System.Xml.XPath.XsltFunction.ReturnType() at System.Xml.XPath.XsltFunction.get_Function() at System.Xml.XPath.XsltFunction.ReturnType() at System.Xml.XPath.XPathNavigator.Evaluate(XPathExpression expr, XPathNodeIterator context) at System.Xml.Xsl.Processor.ValueOf(ActionFrame context, Int32 key) at System.Xml.Xsl.ValueOfAction.Execute(Processor processor, ActionFrame frame) at System.Xml.Xsl.ActionFrame.Execute(Processor processor) at System.Xml.Xsl.Processor.Execute() at System.Xml.Xsl.XslTransform.Transform(XPathNavigator input, XsltArgumentList args, TextWriter output, XmlResolver resolver) at Sitecore.WebControls.XslFile.DoRender(HtmlTextWriter output) Xsl file could not be processed: /xsl/DTU Breadcrumb.xslt
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Referenceliste
Nedenfor fremgår de væsentligste bøger og øvrige publikationer, som dette materiale er baseret på og som kan inspirere videre.

Væsentlige referencer for teori-materialet og inspiration til videre læsning

 

Bemærk, at de fleste materialer er på engelsk og som udgangspunkt ikke frit tilgængelige på internettet.

 

1. Hvad er DNA og gener?

Grundlæggende lærebøger i molekylær biologi:

  • Life: The Science of Biology. 2006. Sadava, D; Heller, HC; Orians, GH; Purves, WK; Hillis, DM. 8. udgave. W. H. Freeman
  • Molecular Cell Biology. 2007. Lodish, H; Berk, A; Kaiser, CA; Krieger, M; Scott, MP; Bretscher, A; Ploegh, H; Matsudaira, P. 6. udgave. W. H. Freeman
  • Molecular Genetics of Bacteria. 2007. Snyder, L; Champness, W. 3. udgave. ASM Press

2. Cellefabrikker - Den bioteknologiske rute fra DNA til protein

Grundlæggende lærebøger som før, samt specifikt:

  • Principles of Fermentation Technology. 1999. Stanbury, PF; Hall, S; Whitaker, 2. udgave. A. Butterworth-Heinemann. Forklarering af fermentering og oprensning.
  • Wurm, FM. 2004. Production of recombinant protein therapeutics in cultivated mammalian cells. Nature biotechnology, vol:22,iss:11.pp 1393-1398.
  • Nielsen, J. 2001. Metabolic engineering. Applied microbiology and biotechnology. vol:55, iss:3,pp:263-283. Introduktion til forbedringsmulighederne af celler med metabolic engineering.
  • Life: The Science of Biology. 2006. Sadava, D; Heller, HC; Orians, GH; Purves, WK; Hillis, DM. 8. udgave. W. H. Freeman. Chapter 14?
  • Man tager et gen..., 1994. Novo Nordisk.
  • Beekwilder, et al. 2006. Production of resveratrol in recombinant microorganisms. Applied and environmental microbiology, vol:72,iss:8,pp:5670-5672.
  • Cleetham, JC et al. 1998. NMR structure of human erythropoietin and a comparison with its receptor bound conformation. Nature structural biology. Vol:5,iss:10,pp:861-866.

3. Genetisk tuning af cellefabrikker

  • Hannig, G; Makrides, S. 1998. Strategies for optimizing heterologous protein expression in Escherichia coli. Trends in biotechnology. vol:16,iss:2,pp:54-60.
  • Sørensen, HP; Mortensen, KK. 2005. Advanced genetic strategies for recombinant protein expression in Escherichia coli. Journal of biotechnology. vol:115,iss:2,pp:113-128.
  • Hengen, PN. 1995. Purification of His-Tag fusion proteins from Escherichia coli. Trends in biochemical sciences. vol:20,iss:7,pp:285-286.

 

4. Genteknologiske værktøjer

 

Grundlæggende lærebog for genteknologiske værktøjer:

  • Molecular Biotechnology - Principles and Applications of Recombinant DNA. 2002. Glick, BR; Pasternak, JJ. 3. udgave. ASM Press
  • Molecular Biotechnology - Principles and Applications of Recombinant DNA. 2009. Glick, BR; Pasternak, JJ; Patten, CL. 4. udgave. ASM Press

  Kemisk DNA-syntese:

  • TAG Copenhagen. 26-09-2010. Product Description oligonucleotides. Link

  DNA-sekventering:

  • Metzker, ML. 2010. Sequencing technologies - the next generation. Nature reviews genetics, vol:11,iss:1,pp:31-46.

Syntetisk biologi:

  • Panke, Sven. 2008. Synthetic Biology - Engineering in Biotechnology, ETH Zürich. Link. Særligt anbefalesværdig.
  • Alper, J. 2009. Biotech in the basement. Nature Biotechnology. vol:27,iss:12,pp:1077-1078
  • Focus issue, dec 2009. Synthetic Biology. Nature Biotechnology, vol:27, iss:12, Særligt pp:1091-1111. Link.
  • What Is Life?: Investigating the Nature of Life in the Age of Synthetic Biology. 2008. Regis, Ed. 1. udgave. Farrar, Straus and Giroux. 

 

Etik og lovgivning i genteknologi

  • Phillips, T. 2008. Genetically modified organisms (GMOs): Transgenic crops and recombinant DNA technology. Nature Education vol:1,iss:1
  • Ministeriet for Videnskab, Teknologi og Udvikling. 2003. Genmodificerede og klonede dyr. Kapitel 3. Version 1.0 Link.
  • Ministeriet for Fødevarer, Landbrug og Fiskeri. 07-10-2010. Website om Genetisk Modificerede Organismer (GMO). Link.

Cases:

 

Insekttolerant bomuld

  • Subramanian, A et al. 2010. GM crops and gender issues. Nature biotechnology, vol:28,iss:5,pp:404-406.
  • Damgaard, C et al. 2005. Genmodificerede planter. Danmarks Miljøundersøgelser og forlaget Hovedland. 2. udgave. Link
  • Lu, Y et al. 2010. Mirid Bug Outbreaks in Multiple Crops Correlated with Wide-Scale Adoption of Bt Cotton in China. Science, vol:328,iss:5982,pp:1151-1154
  • Sharma, DC. 2010. Bt cotton has failed admits Monsanto. India Today. Link

 

Gylden ris 2.0

  • Paine, JA et al. 2005. Improving the nutritional value of Golden Rice through increased pro-vitamin A content. Nature biotechnology, vol:23,iss:4,pp:482-487.
  • Potrykus, I. 2010. Regulation must be revolutionized. Nature, vol:466,iss:7306,pp:561.
  • Meyer, G. 2001. Gylden ris har lang rejse foran sig. Nyt fra Center for bioetik og risikovurdering, KVL. 2. årgang, 3. nr. Link.

Geden som en moderne medicinfabrik

  • Edmunds, T et al. 1998. Transgenically Produced Human Antithrombin: Structural and Functional Comparison to Human Plasma-Derived Antithrombin. Blood, vol:91,iss:12,pp:4561-4571. Link
  • Nielsen, RH. 2006. Vejen er banet for nye billige lægemidler produceret af dyr. Ingeniøren, Link
  • Choi, C. 2009. ATryn, on Old MacDonald's Pharm. Scientific American. Link

Genteknologi og medicinproduktion

 

Genteknologi og enzymer

Sidst opdateret 12.11.2011
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System.Xml.Xsl.XsltException: Cannot find the script or external object that implements prefix 'util'. at System.Xml.Xsl.XsltCompileContext.ResolveFunction(String prefix, String name, XPathResultType[] argTypes) at System.Xml.XPath.XsltFunction.get_Function() at System.Xml.XPath.XsltFunction.ReturnType() at System.Xml.XPath.CompiledXpathExpr.get_ReturnType() at System.Xml.Xsl.Processor.RunQuery(ActionFrame context, Int32 key) at System.Xml.Xsl.VariableAction.Execute(Processor processor, ActionFrame frame) at System.Xml.Xsl.ActionFrame.Execute(Processor processor) at System.Xml.Xsl.Processor.Execute() at System.Xml.Xsl.XslTransform.Transform(XPathNavigator input, XsltArgumentList args, TextWriter output, XmlResolver resolver) at Sitecore.WebControls.XslFile.DoRender(HtmlTextWriter output) Xsl file could not be processed: /xsl/DTU BottomAddress.xslt